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1

Interferon-α and antisense K-ras RNA combination gene therapy against pancreatic cancer

Kazuteru Hatanaka, Koichi Suzuki, Yoshiaki Miura, Kimiko Yoshida, Shumpei Ohnami, Yukio Kitade, Teruhiko Yoshida, Kazunori Aoki

Journal:

The Journal of Gene Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 208 KB

english, 2004

2

Intratumoral interferon-α gene transfer enhances tumor immunity after allogeneic hematopoietic stem cell transplantation

Hidehiko Hara, Akihiko Kobayashi, Kenta Narumi, Atsushi Kondoh, Kimiko Yoshida, Takeshi Nishimoto, Masaki Ohashi, Eiji Higashihara, Shumpei Ohnami, Teruhiko Yoshida, Kazunori Aoki

Journal:

Cancer Immunology, Immunotherapy

Année:

2009

Langue:

english

Fichier:

PDF, 624 KB

english, 2009

3

Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples

Kimio Yoshimura, Tomoyuki Hanaoka, Shumpei Ohnami, Sumiko Ohnami, Takashi Kohno, Ying Liu, Teruhiko Yoshida, Hiromi Sakamoto, Shoichiro Tsugane

Journal:

Journal of Human Genetics

Année:

2003

Langue:

english

Fichier:

PDF, 177 KB

english, 2003

4

Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples

Ying Liu, Kimio Yoshimura, Tomoyuki Hanaoka, Shumpei Ohnami, Sumiko Ohnami, Takashi Kohno, Teruhiko Yoshida, Hiromi Sakamoto, Tomotaka Sobue, Shoichiro Tsugane

Journal:

Journal of Human Genetics

Année:

2005

Langue:

english

Fichier:

PDF, 208 KB

english, 2005

5

Gene expression profiles of endothelial progenitor cells by oligonucleotide microarray analysis

Souichi Furuhata, Kiyoshi Ando, Masayuki Oki, Kazunori Aoki, Shunsuke Ohnishi, Kazuhiko Aoyagi, Hiroki Sasaki, Hiromi Sakamoto, Teruhiko Yoshida, Shumpei Ohnami

Journal:

Molecular and Cellular Biochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 431 KB

english, 2007

6

Development of gene therapy to target pancreatic cancer

Teruhiko Yoshida, Shumpei Ohnami, Kazunori Aoki

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2004

7

Local interferon-α gene therapy elicits systemic immunity in a syngeneic pancreatic cancer model in hamster

Hidehiko Hara, Akihiko Kobayashi, Kimiko Yoshida, Masaki Ohashi, Shumpei Ohnami, Eiji Uchida, Eiji Higashihara, Teruhiko Yoshida, Kazunori Aoki

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 424 KB

english, 2007

8

Administration route-dependent induction of antitumor immunity by interferon-alpha gene transfer

Kenta Narumi, Atsushi Kondoh, Takeshi Udagawa, Hidehiko Hara, Naoko Goto, Yoshinori Ikarashi, Shumpei Ohnami, Toshihide Okada, Masakazu Yamagishi, Teruhiko Yoshida, Kazunori Aoki

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 696 KB

english, 2010

9

Expression profiles of pancreatic cancer cell lines infected with antisense K-ras-expressing adenoviral vector

Shumpei Ohnami, Kazunori Aoki, Kimiko Yoshida, Sumiko Ohnami, Kazuteru Hatanaka, Koichi Suzuki, Hiroki Sasaki, Teruhiko Yoshida

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 137 KB

english, 2003

10

Intraperitoneal injection of adenovirus expressing antisense K-ras RNA suppresses peritoneal dissemination of hamster syngeneic pancreatic cancer without systemic toxicity

Yoshiaki Miura, Shumpei Ohnami, Kimiko Yoshida, Masaki Ohashi, Masaru Nakano, Sumiko Ohnami, Munehisa Fukuhara, Ken Yanagi, Akira Matsushita, Eiji Uchida, Masahiro Asaka, Teruhiko Yoshida, Kazunori Ao

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 284 KB

english, 2005

11

Adenovirus-mediated gene transfer of interferon α inhibits hepatitis C virus replication in hepatocytes

Koichi Suzuki, Kazunori Aoki, Shumpei Ohnami, Kimiko Yoshida, Teruhisa Kazui, Nobuyuki Kato, Kazuaki Inoue, Michinori Kohara, Teruhiko Yoshida

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 169 KB

english, 2003

12

His595Tyr Polymorphism in the Methionine Synthase Reductase (MTRR) Gene Is Associated With Pancreatic Cancer Risk

Shumpei Ohnami, Yasunori Sato, Kimio Yoshimura, Sumiko Ohnami, Hiromi Sakamoto, Kazunori Aoki, Hideki Ueno, Masafumi Ikeda, Chigusa Morizane, Kazuaki Shimada, Yoshihiro Sakamoto, Minoru Esaki, Ikuo Sa

Journal:

Gastroenterology

Année:

2008

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2008

13

Development of a Novel Efficient Method To Construct an Adenovirus Library Displaying Random Peptides on the Fiber Knob

Yamamoto, Yuki, Goto, Naoko, Miura, Kazuki, Narumi, Kenta, Ohnami, Shumpei, Uchida, Hiroaki, Miura, Yoshiaki, Yamamoto, Masato, Aoki, Kazunori

Journal:

Molecular Pharmaceutics

Année:

2014

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2014

14

16. Direct Selection of Targeted Vector from a Random Peptide Library Displayed on Adenoviral Fiber Knob

Aoki, Kazunori, Miura, Yoshiaki, Yoshida, Kimiko, Hatanaka, Kazuteru, Nishimoto, Takeshi, Ohnami, Shumpei, Douglas, Joanne T., Curiel, David T., Yoshida, Teruhiko

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 82 KB

english, 2006

15

Analysis of Human Pituitary and Tumor Adrenocorticotropin Using Isoelectric Focusing*

TANAKA, NOBUYOSHI, ABE, KAORU, MIYAKAWA, SUMIKO, OHNAMI, SHUMPEI, TANAKA, MASAHIRO, TAKEUCHI, TOSHIYUKI

Journal:

Journal of Clinical Endocrinology & Metabolism

Année:

1979

Langue:

english

Fichier:

PDF, 714 KB

english, 1979

16

β-Melanocyte-Stimulating Hormone Immunoreactivity in Human Pituitaries and Ectopic Adrenocorticotropin-Producing Tumors*

UEDA, MASAKAZU, TAKEUCHI, TOSHIYUKI, ABE, KAORU, MIYAKAWA, SUMIKO, OHNAMI, SHUMPEI, YANAIHARA, NOBORU

Journal:

Journal of Clinical Endocrinology & Metabolism

Année:

1980

Langue:

english

Fichier:

PDF, 788 KB

english, 1980

17

Characterization of “Big Big Prolactin” in Serum and Tumor Extract in Patients with PRL-Secreting Tumor

OHNAMI, SHUMPEI, ETO, SUMIYA, OHNAMI, SUMIKO, SOEJIMA, TOHRU, NAKATA, HAJIME

Journal:

Endocrinologia Japonica

Année:

1987

Langue:

english

Fichier:

PDF, 2.60 MB

english, 1987

18

Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors

Ohnami, Shumpei, Ohshima, Keiichi, Nagashima, Takeshi, Urakami, Kenichi, Shimoda, Yuji, Saito, Junko, Naruoka, Akane, Hatakeyama, Keiichi, Mochizuki, Tohru, Serizawa, Masakuni, Ohnami, Sumiko, Kusuhar

Journal:

Molecular and Cellular Biochemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2017

19

Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors

Ohshima, Keiichi, Hatakeyama, Keiichi, Nagashima, Takeshi, Watanabe, Yuko, Kanto, Kaori, Doi, Yuki, Ide, Tomomi, Shimoda, Yuji, Tanabe, Tomoe, Ohnami, Sumiko, Ohnami, Shumpei, Serizawa, Masakuni, Maru

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 7.85 MB

english, 2017

20

Germline and somatic genetic changes in multicentric tumors obtained from a patient with multiple endocrine neoplasia type 1

Naruoka, Akane, Ohnami, Sumiko, Nagashima, Takeshi, Serizawa, Masakuni, Ohshima, Keiichi, Ohnami, Shumpei, Urakami, Kenichi, Horiuchi, Yasue, Kiyozumi, Yoshimi, Abe, Masato, Nakajima, Takashi, Sugiura

Journal:

Human Genome Variation

Année:

2017

Langue:

english

Fichier:

PDF, 2.08 MB

english, 2017

21

Prevalence of low-penetrant germline TP53 D49H mutation in Japanese cancer patients

YAMAGUCHI, Ken, URAKAMI, Kenichi, NAGASHIMA, Takeshi, SHIMODA, Yuji, OHNAMI, Shumpei, OHNAMI, Sumiko, OHSHIMA, Keiichi, MOCHIZUKI, Tohru, HATAKEYAMA, Keiichi, SERIZAWA, Masakuni, AKIYAMA, Yasuto, MARU

Journal:

Biomedical Research

Année:

2016

Langue:

english

Fichier:

PDF, 221 KB

english, 2016

22

Immune response-associated gene analysis of 1,000 cancer patients using whole-exome sequencing and gene expression profiling—Project HOPE—

AKIYAMA, Yasuto, KONDOU, Ryota, IIZUKA, Akira, OHSHIMA, Keiichi, URAKAMI, Kenichi, NAGASHIMA, Takeshi, SHIMODA, Yuji, TANABE, Tomoe, OHNAMI, Sumiko, OHNAMI, Shumpei, KUSUHARA, Masatoshi, MOCHIZUKI, To

Journal:

Biomedical Research

Année:

2016

Langue:

english

Fichier:

PDF, 3.80 MB

english, 2016

23

Whole exome sequencing detects variants of genes that mediate response to anticancer drugs

Ohnami, Sumiko, Nagashima, Takeshi, Urakami, Kenichi, Shimoda, Yuji, Kamada, Fukumi, Saito, Junko, Naruoka, Akane, Serizawa, Masakuni, Masuda, Yoko, Ohnami, Shumpei, Kusuhara, Masatoshi, Yamaguchi, Ke

Journal:

The Journal of Toxicological Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2017

24

Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations

Hatakeyama, Keiichi, Ohshima, Keiichi, Nagashima, Takeshi, Ohnami, Shumpei, Ohnami, Sumiko, Serizawa, Masakuni, Shimoda, Yuji, Maruyama, Koji, Akiyama, Yasuto, Urakami, Kenichi, Kusuhara, Masatoshi, M

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2018

25

Tumor mutational burden analysis of 2,000 Japanese cancer genomes using whole exome and targeted gene panel sequencing

HATAKEYAMA, Keiichi, NAGASHIMA, Takeshi, URAKAMI, Kenichi, OHSHIMA, Keiichi, SERIZAWA, Masakuni, OHNAMI, Sumiko, SHIMODA, Yuji, OHNAMI, Shumpei, MARUYAMA, Koji, NARUOKA, Akane, AKIYAMA, Yasuto, KUSUHA

Journal:

Biomedical Research

Année:

2018

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2018

26

Development of Peritoneal Tumor-Targeting Vector by In Vivo Screening with a Random Peptide-Displaying Adenovirus Library

Nishimoto, Takeshi, Yamamoto, Yuki, Yoshida, Kimiko, Goto, Naoko, Ohnami, Shumpei, Aoki, Kazunori, Ulasov, Ilya

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 486 KB

english, 2012

27

Next generation sequencing approach for detecting 491 fusion genes from human cancer

URAKAMI, Kenichi, SHIMODA, Yuji, OHSHIMA, Keiichi, NAGASHIMA, Takeshi, SERIZAWA, Masakuni, TANABE, Tomoe, SAITO, Junko, USUI, Tamiko, WATANABE, Yuko, NARUOKA, Akane, OHNAMI, Sumiko, OHNAMI, Shumpei, M

Journal:

Biomedical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1002 KB

english, 2016

28

Optimizing an ion semiconductor sequencing data analysis method to identify somatic mutations in the genomes of cancer cells in clinical tissue samples

NAGASHIMA, Takeshi, SHIMODA, Yuji, TANABE, Tomoe, NARUOKA, Akane, SAITO, Junko, SERIZAWA, Masakuni, OHSHIMA, Keiichi, URAKAMI, Kenichi, OHNAMI, Sumiko, OHNAMI, Shumpei, MOCHIZUKI, Tohru, KUSUHARA, Mas

Journal:

Biomedical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2016

29

Mutational burden and signatures in 4,000 Japanese cancers provide insights into tumorigenesis and response to therapy

Hatakeyama, Keiichi, Nagashima, Takeshi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Serizawa, Masakuni, Maruyama, Koji, Naruoka, Akane, Akiyama, Yasuto, Urakami, Kenichi, Kusuha

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2019

30

The presence of macromolecular vasoactive intestinal polypeptide (VIP) in VIP-producing tumors

Yamaguchi, Ken, Abe, Kaoru, Miyakawa, Sumiko, Ohnami, Shumpei, Sakagami, Masanori, Yanaihara, Noboru

Journal:

Gastroenterology

Année:

1980

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1980

31

Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors

Ohshima, Keiichi, Fujiya, Keiichi, Nagashima, Takeshi, Ohnami, Sumiko, Hatakeyama, Keiichi, Urakami, Kenichi, Naruoka, Akane, Watanabe, Yuko, Moromizato, Sachi, Shimoda, Yuji, Ohnami, Shumpei, Serizaw

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.38 MB

english, 2019

32

Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors

Ohshima, Keiichi, Fujiya, Keiichi, Nagashima, Takeshi, Ohnami, Sumiko, Hatakeyama, Keiichi, Urakami, Kenichi, Naruoka, Akane, Watanabe, Yuko, Moromizato, Sachi, Shimoda, Yuji, Ohnami, Shumpei, Serizaw

Journal:

Année:

2019

Fichier:

PDF, 2.38 MB

2019

33

Characterization of tumors with ultralow tumor mutational burden in Japanese cancer patients

Hatakeyama, Keiichi, Nagashima, Takeshi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Naruoka, Akane, Maruyama, Koji, Iizuka, Akira, Ashizawa, Tadashi, Mochizuki, Tohru, Urakami,

Journal:

Année:

2020

Fichier:

PDF, 2.20 MB

2020